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Nicosulfuron in Corn: Selective Post-Emergence Grass Weed Control That Works

Weed competition is one of the biggest yield-limiting factors in corn production—especially from annual and perennial grasses that establish early and rob the crop of nutrients, light, and water. For decades, post-emergence control has been a strategic part of maize weed management, and nicosulfuron has become one of the most trusted active ingredients in this category.

A systemic sulfonylurea herbicide, nicosulfuron offers selective control of key grass weeds in maize without harming the crop. Whether used alone or in tank mixes with complementary herbicides, it allows growers to target weeds at the most vulnerable stages, ensuring cleaner fields and stronger crop establishment.

In this article, we’ll explore how nicosulfuron works, what weeds it controls, how to apply it in maize fields, and what precautions to take for safe and effective use—especially if you’re sourcing or formulating nicosulfuron 40g/L SC or other combinations for your agricultural market.

What Is Nicosulfuron and How It Works in Corn

Nicosulfuron is a selective post-emergence herbicide belonging to the sulfonylurea chemical family, classified under HRAC Group B (ALS inhibitors). It is specifically designed to control a wide range of grass weeds and some broadleaf species in field corn (maize). Its systemic mode of action makes it a highly effective solution for early-season weed management.


Mode of Action

Nicosulfuron inhibits the enzyme acetolactate synthase (ALS), also known as acetohydroxy acid synthase (AHAS). This enzyme is essential for the synthesis of branched-chain amino acids (valine, leucine, isoleucine) in plants. When ALS is blocked:

  • Cell division and growth stop rapidly

  • Treated weeds cease development within hours

  • Visible symptoms—such as chlorosis and necrosis—appear within 3 to 10 days

  • Complete weed death typically occurs within 2 to 3 weeks

Because this enzyme is not present in animals, nicosulfuron has a favorable toxicological profile and can be used safely when applied according to label guidelines.


Selectivity in Corn

Nicosulfuron is absorbed mainly through the foliage and translocated throughout the weed. Corn plants metabolize the active ingredient rapidly, preventing herbicidal damage. This makes it safe to use on tolerant maize hybrids during specific growth stages—especially from V2 to V6 (2- to 6-leaf stage).

Target Weeds Controlled by Nicosulfuron

Nicosulfuron is particularly effective against a broad spectrum of annual and perennial grass weeds, which are among the most competitive and difficult to manage in corn fields. It also provides partial control of some broadleaf weeds, especially when tank-mixed with compatible herbicides.


Key Grass Weeds Controlled

  • Echinochloa crus-galli (Barnyardgrass)

  • Setaria spp. (Foxtail species: green, yellow, giant)

  • Digitaria spp. (Crabgrass)

  • Panicum spp. (Fall panicum, witchgrass)

  • Sorghum halepense (Johnsongrass, seedling and rhizome forms)

  • Lolium spp. (Ryegrass)

  • Avena fatua (Wild oat) – at early stages


Broadleaf Weeds with Suppression or Partial Control

  • Amaranthus spp. (Pigweed)

  • Chenopodium album (Lambsquarters)

  • Portulaca oleracea (Purslane)

  • Polygonum spp. (Smartweed)

  • Galinsoga parviflora (Gallant soldier)

For enhanced control of broadleaf weeds, nicosulfuron is often tank-mixed with atrazine, dicamba, mesotrione, or bromoxynil, depending on crop stage and regional regulation.


Weed Growth Stage Matters

Nicosulfuron is most effective when target weeds are small and actively growing, typically in the 2–4 leaf stage. Applications to mature, stressed, or drought-hardened weeds may reduce efficacy. For perennial weeds like Johnsongrass from rhizomes, early post-emergence treatment (15–30 cm height) is critical for suppression.

Application Timing, Rates, and Techniques in Corn

To maximize the effectiveness and crop safety of nicosulfuron, precise timing and application technique are essential. As a post-emergence systemic herbicide, it must be applied when both the corn crop and the target weeds are at appropriate growth stages.


Recommended Timing

  • Corn growth stage: Apply when corn is at V2 to V6 stage (2 to 6 visible leaves)

  • Weed growth stage: Apply when grasses are small (2–4 leaf stage) and actively growing

  • Avoid application under stress conditions such as drought, cold temperatures, or after another herbicide that might weaken corn metabolism


Typical Application Rates

Formulation Recommended Rate Remarks
Nicosulfuron 40g/L SC 1.0 – 1.5 L/ha Based on weed pressure and crop size
Nicosulfuron 4% OD 0.75 – 1.25 L/ha Emulsifiable for broader compatibility
Technical equivalence 30 – 60 g a.i./ha Adjust for tank-mix and product purity

Always check local label recommendations, as rates may vary by country, crop type, and herbicide formulation.


Application Method and Carrier Volume

  • Apply via ground sprayer or tractor-mounted boom, ensuring uniform coverage

  • Use clean water, carrier volume of 200–400 L/ha for optimal leaf coverage

  • Nozzles: Use flat-fan or air-induction nozzles to avoid drift

  • Rainfastness: Rain within 2–4 hours may reduce efficacy—ensure adequate dry time


Tank Mixing and Adjuvants

  • Adjuvants: A non-ionic surfactant (NIS) or methylated seed oil (MSO) can improve uptake, especially on waxy or stressed weeds

  • Tank-mix partners: Atrazine, mesotrione, dicamba, bromoxynil (based on weed spectrum)

  • Compatibility check: Always conduct a jar test before mixing with other products

Advantages of Using Nicosulfuron in Corn Fields

Nicosulfuron has earned a strong reputation among corn growers and crop protection professionals for its reliable, selective, and efficient control of grassy weeds. Its widespread adoption in global maize production systems is driven by several agronomic and economic benefits.


1. Excellent Crop Selectivity

  • Specifically formulated for use in field corn (Zea mays)

  • Minimal phytotoxicity when applied at recommended growth stages

  • Safe for most conventional and herbicide-tolerant hybrids

  • Rapid corn metabolism prevents accumulation in crop tissues


2. Strong Systemic Control of Grass Weeds

  • Effective against both annual and perennial grasses, including difficult species like Johnsongrass and foxtail

  • Moves within the plant to reach underground growing points, preventing regrowth

  • Offers longer-lasting control than contact-only herbicides


3. Flexible Tank Mix Compatibility

  • Compatible with broadleaf herbicides such as atrazine, mesotrione, dicamba

  • Can be integrated into customized broad-spectrum post-emergence programs

  • Works well with adjuvants and nutritional foliar feeds, reducing passes and operational costs


4. Low Application Rate and Environmental Load

  • Applied at low active ingredient rates (30–60 g a.i./ha)

  • Lower risk of groundwater contamination compared to older herbicides

  • Low odor, low vapor pressure, and reduced risk to non-target organisms


5. Proven Performance Across Diverse Climates

  • Effective in temperate, subtropical, and tropical maize systems

  • Widely adopted in Latin America, Eastern Europe, North Africa, and Asia

  • Stable across different soil types and moisture conditions, when weeds are actively growing

Limitations and Crop Safety Considerations

While nicosulfuron is a highly effective and selective herbicide for corn, its performance and safety depend on correct use, appropriate timing, and crop sensitivity awareness. Improper application can reduce efficacy or cause crop injury, especially under stress conditions or when used on non-tolerant varieties.


1. Not Suitable for All Corn Types

  • Do not use nicosulfuron on:

    • Sweet corn (Zea mays saccharata)

    • Popcorn varieties

    • Any non-tolerant hybrids without label confirmation

These types lack the metabolic pathways needed to detoxify nicosulfuron, making them highly susceptible to herbicide injury.


2. Environmental Stress Increases Risk of Phytotoxicity

Avoid applying nicosulfuron under or immediately after:

  • Cold stress (temperatures below 10°C)

  • Drought or waterlogging

  • Nutrient-deficient soils or compacted zones

  • Other ALS-inhibiting herbicides used in pre-emergence phase

These conditions can reduce the corn plant’s ability to metabolize the active ingredient, increasing the risk of yellowing, stunting, or delayed growth.


3. Soil pH and Residual Activity

  • Nicosulfuron has limited residual activity, making it safer for rotation

  • However, in soils with high pH (>7.5) and low organic matter, carryover potential increases, especially in dry years

  • Be cautious if rotating to sensitive crops such as sugar beet, beans, or sunflower


4. Risk of Herbicide Resistance

  • Nicosulfuron is an ALS inhibitor, and overreliance on this mode of action can lead to resistance

  • Several grass weed populations worldwide have developed ALS resistance

  • Always rotate with herbicides from different HRAC groups to maintain long-term effectiveness

Nicosulfuron Formulations and Our Supply Capabilities

As a professional agrochemical manufacturer and exporter, we offer a full range of nicosulfuron-based herbicide formulations tailored for use in post-emergent weed control in corn. Our products are available in multiple concentrations and can be customized to suit your local market demands, registration needs, and packaging requirements.


Available Formulations

1. Nicosulfuron 40 g/L SC (Suspension Concentrate)

  • Most widely used post-emergent formulation for corn

  • Offers excellent crop safety and broad grass weed control

  • Designed for easy tank mixing with broadleaf herbicides

2. Nicosulfuron 4% OD (Oil Dispersion)

  • Enhanced uptake on waxy-leafed grasses

  • Compatible with non-ionic surfactants and MSO adjuvants

  • Suitable for dryland and high-evaporation environments

3. Nicosulfuron Combinations (upon request)

  • Custom-formulated mixes with atrazine, dicamba, mesotrione, or bromoxynil

  • Designed to expand the weed control spectrum and reduce application complexity

  • Available as SC, OD, or EW based on market registration


Our Manufacturing and OEM Services

We support a wide range of partners across Latin America, Africa, Eastern Europe, and Asia with:

  • Flexible packaging: 100 mL to 20 L bottles, bulk supply in drums or IBCs

  • Private labeling: Full OEM/ODM capability with multilingual design support

  • Regulatory documentation: MSDS, COA, TDS, sample labels, and dossiers

  • Stable supply chain: On-time delivery, strict QC, and support for tender bids

Whether you're expanding your post-emergent herbicide portfolio or building a new corn-focused weed control line, our technical and export teams are ready to deliver cost-effective, reliable, and fully customized nicosulfuron solutions.

FAQ: Common Questions About Nicosulfuron Use in Corn

1. Can nicosulfuron be safely used on all types of corn?

No. Nicosulfuron is safe for field corn hybrids that are tolerant to sulfonylurea herbicides. It should not be used on sweet corn, popcorn, or non-labeled hybrids, as these may experience significant crop injury.


2. What weeds does nicosulfuron control best?

It is highly effective against annual and perennial grass weeds such as:

  • Foxtails (Setaria spp.)

  • Barnyardgrass (Echinochloa spp.)

  • Crabgrass (Digitaria spp.)

  • Johnsongrass (Sorghum halepense)

  • It also offers partial suppression of certain broadleaf weeds, especially when tank-mixed.


3. Can nicosulfuron be tank-mixed with other herbicides?

Yes. It is commonly mixed with atrazine, mesotrione, dicamba, or bromoxynil to broaden the weed control spectrum. Always perform a jar test for physical compatibility and follow local label instructions for approved mixtures.


4. How soon after application can I see results?

Weeds typically stop growing within 24–48 hours. Visible symptoms such as yellowing and necrosis appear in 3–10 days, with full control achieved within 2–3 weeks.


5. Is nicosulfuron affected by rainfall?

Nicosulfuron is rainfast within 2 to 4 hours after application. For best results, avoid spraying if rain is expected shortly after treatment.


6. What are the re-cropping or rotation restrictions?

Because of its ALS-inhibiting mode of action, avoid planting sensitive crops (e.g., sugar beets, pulses, sunflowers) within 6–12 months, depending on soil pH and rainfall. Always refer to local guidelines for rotation intervals.

Conclusion: Is Nicosulfuron Right for Your Corn Weed Management Strategy?

If you're managing post-emergence grass weed pressure in corn, nicosulfuron remains one of the most reliable, selective, and cost-effective solutions available. With its systemic mode of action, low application rate, and excellent crop safety, it delivers consistent results across diverse maize production systems—whether you're growing under conventional, conservation tillage, or irrigation-based conditions.

When applied correctly and integrated into a well-designed weed control program, nicosulfuron offers:

  • Effective control of major grass weeds and select broadleaves

  • Compatibility with other herbicides for customized spectrum coverage

  • Proven crop tolerance in field corn

  • Flexible formulation options for different market and climate needs

  • A key tool for resistance management and sustainable production

If you're sourcing nicosulfuron 40 g/L SC, developing tank-mix herbicide lines, or expanding your post-emergence portfolio for maize, our team can support you with high-quality formulations, OEM services, and registration-ready documentation tailored to your region.

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