Overall toxicity profile: pendimethalin is generally low in acute toxicity to dogs under normal, labeled use; risk increases with ingestion of concentrates or granules and with certain co-formulants/solvents.
Most expected acute signs from real-world exposures: GI upset (drooling, vomiting, diarrhea), transient lethargy/ataxia, and dermal/ocular irritation; concentrated product exposures can be more severe.
Practical risk window: highest before spray dries or granules are watered-in; risk typically declines once surfaces are dry/inaccessible. Follow the product label for pet re-entry.
Red-flag symptoms that warrant urgent veterinary attention: repeated vomiting, breathing difficulty, tremors/seizures, marked lethargy, eye pain, or unknown/large amount ingestion.
What owners should have ready for the vet: product name/label, active concentration, estimated amount, time since exposure, and observed signs.
Everyday risk reduction: keep pets away during application, allow full drying (or water-in granules as directed), secure storage/cleanup, and prevent paw-licking from freshly treated areas.
Prognosis framing: incidental, low-level contact is often mild and self-limited; concentrate/large-amount ingestion deserves prompt veterinary assessment.
Primary routes for dogs: oral (paw-grooming after walking on treated turf, licking freshly sprayed blades, ingesting granules or diluted mix), dermal/ocular contact, and aerosol/mist inhalation during application.
Relative risk by product/form: highest with ingestion of concentrates (EC/SC) and co-formulants; moderate with swallowing granules; lower with incidental contact to dry turf or diluted residues once fully dried and inaccessible.
Role of co-formulants: solvents/surfactants in some EC/SC products can add GI upset and local irritation beyond the active ingredient; dyes may cause temporary staining without indicating severity.
Wet vs dry surfaces: risk is greatest before spray dries or before granules are watered-in; transfer potential declines markedly after complete drying or thorough watering-in with no standing water.
Re-entry cues for pets: keep dogs away during application; allow full drying of sprayed areas; for granules, finish watering-in as directed and wait until the grass/soil is dry to the touch; follow the specific product label for pet re-entry.
Secondary exposure pathways: track-in from shoes/equipment, puddles on patios/paths, or access to spreader hoppers/empty bags; confine pets until gear is cleaned and storage is secured.
Practical housekeeping: after incidental outdoor contact, wipe paws and undercarriage; prevent drinking from runoff or puddles near recently treated zones.
Oral ingestion (most common): From paw-licking or nibbling treated grass to swallowing granules/dilute spray. Typical onset within minutes to a few hours. Signs: drooling, nausea, vomiting, diarrhea, transient lethargy/ataxia; concentrates may add stronger GI irritation and occasionally disorientation. Duration is usually hours to 24–48 h for incidental doses.
Dermal exposure: Contact with wet turf, wet soil, or spilled product. Onset immediate to ≤2 h. Signs: erythema, pruritus, mild warmth, cosmetic yellow/orange staining from dyes; discomfort generally self-limited after washing once dry.
Ocular exposure: Splash or rubbing face on freshly treated vegetation. Onset immediate. Signs: tearing, squinting, conjunctival redness, foreign-body sensation; corneal irritation may cause marked blepharospasm and light sensitivity.
Inhalation/aerosol: Present mainly during application or in enclosed spaces. Onset minutes. Signs: coughing, sneezing, throat irritation, transient tachypnea; resolves after fresh air once the area is clear and dry.
Severity modifiers: Amount and concentration (EC/SC vs granules vs dry turf), time since application (wet vs fully dry/watered-in), co-formulants (solvents/surfactants), dog size/age, and pre-existing GI/ocular conditions.
Escalation cues: Repeated vomiting, inability to keep water down, worsening lethargy, tremors, unusual breathing, or persistent eye pain require prompt veterinary assessment. Keep product label and exposure details ready.
Remove the dog from the treated area immediately and confine to a clean space; block access to spreaders, empty bags, puddles, or wet turf/soil.
Skin/wet turf contact: wipe paws and coat with a damp cloth; follow with a gentle bath using a pet-safe shampoo; rinse thoroughly and dry; supervise to prevent paw-licking.
Eye contact: flush the affected eye(s) with clean, lukewarm water or sterile saline; avoid rubbing; seek same-day veterinary care if squinting, tearing, or light sensitivity persists.
Suspected ingestion (granules, concentrates, or unknown amount): do not induce vomiting, and do not give home remedies (milk, oils, charcoal, medications) unless a veterinarian or poison control specifically instructs you. Offer fresh water only.
When calling a veterinarian/animal poison control, have ready: product brand/name, formulation (granules, EC/SC), active concentration if listed, time since exposure, estimated amount, whether surfaces were wet/dry/watered-in, observed signs and their timing.
Red-flag situations that warrant urgent professional guidance: ingestion of concentrates or multiple mouthfuls of granules; repeated vomiting or inability to keep water down; breathing difficulty; tremors/ataxia; eye pain or persistent squinting; collapse; very small/young/geriatric dogs; pre-existing medical conditions.
During transport: bring the product container or a clear photo of the full label; secure the dog to prevent further self-exposure (e.g., licking contaminated fur or paws).
Intake priorities: confirm product name/brand, formulation (granules vs EC/SC), active concentration, estimated amount, time since exposure, whether surfaces were wet/dry/watered-in, and current clinical signs.
Risk stratification: concentrates and mixed co-formulants raise concern; ingestion of multiple mouthfuls or unknown amounts, very young/geriatric patients, or pre-existing disease warrant closer monitoring.
Physical exam focus: hydration and perfusion, abdominal comfort, neurologic status (mentation, ataxia, tremors), respiratory pattern, and full ocular exam if face contact occurred (fluorescein stain for corneal injury).
Diagnostic considerations: point-of-care glucose and electrolytes if vomiting/diarrhea; hematocrit/TS for hydration; chemistry panel/urinalysis when ingestion is substantial or signs persist; thoracic imaging only if aspiration is suspected.
Decontamination principles: timely dermal bathing and ocular irrigation when indicated; decisions about GI decontamination are case-by-case and depend on amount, formulation, elapsed time, and aspiration risk.
Supportive care framework: antiemetic and gastroprotective strategies when clinically appropriate; isotonic fluid support for ongoing losses; ocular lubrication and pain control for corneal/conjunctival irritation; calm, thermoneutral housing and serial reassessment.
Monitoring: recheck hydration, electrolytes, and mentation over the first hours; continue observation longer after concentrate exposures or when vomiting recurs. Provide return precautions and written discharge notes referencing the specific product.
Incidental contact with dry, treated turf: typically minimal risk when surfaces are fully dry and inaccessible; brief paw-licking after dry contact is commonly self-limited.
Paw- or coat-licking from wet vegetation or recently watered-in granules: mild GI signs are possible; most uncomplicated cases trend toward short-lived courses once the source is removed and the dog is kept from re-exposure.
Granule ingestion (small known amount): GI upset is the dominant pattern; monitoring for hydration, comfort, and appetite is prudent; escalation is more likely with multiple mouthfuls or unknown amounts.
Concentrate (EC/SC) ingestion or access to mixed spray solution: higher concern due to co-formulants; risk of more pronounced GI and neurologic signs; veterinary assessment is appropriate even if early signs are mild.
Ocular exposure: prognosis is favorable when promptly rinsed; persistent squinting, corneal discomfort, or vision changes warrants same-day examination.
Inhalation/aerosol during application: generally transient upper-airway irritation; recovery is expected after removal to fresh air once the area is cleared and dry.
Patient factors that can worsen outlook: very small/young/geriatric dogs, pre-existing GI, hepatic, ocular, or respiratory disease, and stressful co-exposures (e.g., solvents from other products).
Repeated low-level contact (frequent play on recently treated areas, habitual paw-licking): watch for recurrent GI episodes, weight change, coat/skin irritation between toes, altered activity, or eye discomfort; reduce re-exposure and discuss patterns with a veterinarian.
Keep dogs indoors during mixing and application; remove outdoor bowls, toys, and bedding from treated zones.
Use calm, low-wind windows; avoid spraying near kennels or water sources; close doors/windows to limit drift back indoors.
Sprays: restrict access until fully dry; on first re-entry, wipe paws/underside and block access to puddles or runoff.
Granules: water-in as directed, then keep dogs off until surfaces are dry and loose granules are no longer visible; sweep granules off patios/paths.
Gear & storage: clean spreaders/sprayers outdoors; launder work clothing separately; store products in pet-proof, locked locations; secure empty bags/containers.
Household communication: inform family, dog walkers, and gardeners of treated areas and re-entry timing.
Preparedness: keep product label photos and your veterinarian/animal poison control contacts handy.
Is pendimethalin safe for dogs?
Under labeled use with pets kept away during application and until dry/watered-in, everyday risk is low; highest risk is ingestion of concentrates or multiple mouthfuls of granules.
How long before my dog can go back on the lawn?
After sprays are fully dry; after granules are watered-in and dry to the touch. Always follow the specific product label.
My dog licked pre-emergent/treated grass—what do I do?
Remove from the area, prevent further licking, wipe paws/coat, offer fresh water. Contact your veterinarian or an animal poison control service if vomiting, lethargy, eye discomfort, or unknown amounts are involved.
My dog ate some granules—should I worry?
Swallowing granules warrants professional guidance; bring the product label and estimate the amount and timing.
What if spray got in my dog’s eyes?
Rinse gently with clean, lukewarm water or sterile saline; seek same-day veterinary care if squinting/tearing/light sensitivity persists.
Are dried residues still a concern?
Risk is typically much lower after complete drying; wipe paws on first re-entry and avoid puddles/runoff.
Could there be long-term effects?
With incidental, low-level contact, long-term issues are unlikely. If repeated low-level exposures occur, watch for recurring GI upset, skin/eye irritation, or weight/appetite changes and discuss with your veterinarian.